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2490. A Phase 1, Randomized, Observer Blind, Antigen and Adjuvant Dosage Finding Study to Evaluate the Safety and Immunogenicity of an Adjuvanted, Trivalent Subunit Influenza Vaccine in Elderly Subjects ≥65 Years of Age

BACKGROUND: Influenza virus infection in the elderly remains one of the ten leading causes of death. One successful strategy to enhance the magnitude of their influenza vaccine immune response has been the addition of the adjuvant MF59(®). METHODS: 196 subjects ≥ 65 years of age were enrolled in a d...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Otten, Gillis, Matassa, Vince, Ciarlet, Max, Leav, Brett
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255289/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.2142
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