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The effect of piperlongumine on endothelial and lung adenocarcinoma cells with regulated expression of profilin-1

PURPOSE: The aim of the study was to evaluate the effect of piperlongumine (2 and 4 µM) on endothelial EA.hy926 and lung adenocarcinoma A549 cells with regulated expression of profilin-1 (PFN1). MATERIAL AND METHODS: The cytotoxicity of alkaloid was evaluated by MTT assay, while cell death was asses...

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Bibliografiske detaljer
Udgivet i:Onco Targets Ther
Main Authors: Gagat, Maciej, Hałas-Wiśniewska, Marta, Zielińska, Wioletta, Izdebska, Magdalena, Grzanka, Dariusz, Grzanka, Alina
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255113/
https://ncbi.nlm.nih.gov/pubmed/30538497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S183191
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