Physical Carboxymethylscleroglucan/Calcium Ion Hydrogels as Modified Drug Delivery Systems in Topical Formulations

A carboxymethyl derivative of scleroglucan (Scl-CM) with a 65±5% carboxylic group degree of derivatization (DD) was recently synthesized and characterized. Aqueous solutions of the polymer underwent to a sharp transition toward a gel like behaviour in the presence of divalent ions such as Ca(+2). Ph...

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Bibliographic Details
Published in:Molecules
Main Authors: Corrente, Federica, Matricardi, Pietro, Paolicelli, Patrizia, Tita, Beatrice, Vitali, Federica, Casadei, Maria Antonietta
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255100/
https://ncbi.nlm.nih.gov/pubmed/19701116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules14082684
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