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1402. Cystatin C Improves Estimation of Vancomycin Clearance in Critically Ill Children Using a Population Pharmacokinetic Modeling Approach

BACKGROUND: Vancomycin (VAN) is renally eliminated and clearance (CL) correlates with glomerular filtration rate (GFR). The bedside Schwartz equation (Schwartz(bed)), currently used to estimate GFR in children, relies solely on creatinine (Cr) and is inaccurate in critical illness. We compared the S...

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Bibliografiske detaljer
Udgivet i:Open Forum Infect Dis
Main Authors: Downes, Kevin, Zuppa, Athena
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254693/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1233
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