New Macrocyclic Amines Showing Activity as HIV Entry Inhibitors Against Wild Type and Multi-Drug Resistant Viruses(†)

Considering as a lead molecule the chemokine CXCR4 receptor antagonist AMD-3100, which shows significant anti-HIV activity in vitro and in vivo, we investigated a series of structurally related macrocyclic polyamines incorporating o,o’-phenanthroline or 2,2’-bipyridyl scaffolds as potential antivira...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Rusconi, Stefano, Cicero, Mirko Lo, Viganò, Ottavia, Sirianni, Francesca, Bulgheroni, Elisabetta, Ferramosca, Stefania, Bencini, Andrea, Bianchi, Antonio, Ruiz, Lidia, Cabrera, Cecilia, Martinez-Picado, Javier, Supuran, Claudiu T., Galli, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254439/
https://ncbi.nlm.nih.gov/pubmed/19471212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules14051927
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