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Gene Knockdowns in Adult Animals: PPMOs and Vivo-Morpholinos

Antisense molecules do not readily cross cell membranes. This has limited the use of antisense to systems where techniques have been worked out to introduce the molecules into cells, such as embryos and cell cultures. Uncharged antisense bearing a group of guanidinium moieties on either a linear pep...

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Detalles Bibliográficos
Publicado en:Molecules
Main Authors: Moulton, Jon D., Jiang, Shan
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Diversity Preservation International 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6253989/
https://ncbi.nlm.nih.gov/pubmed/19325525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules14031304
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