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787. The Addition of Avibactam Augments the Activity of Piperacillin Against Mycobacterium abscessus in vitro, and Is Effective in Treating M. abscessus Infection in a Galleria mellonella in vivo Model
BACKGROUND: Mycobacterium abscessus is an emerging multi-drug-resistant pathogen, harboring the β-lactamse Bla(MAB). Avibactam is a non-β-lactam, β-lactamase inhibitor shown to inhibit Bla(MAB) and improve the efficacy of ampicillin for M. abscessus infections in in vitro and in vivo models. Whether...
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| Publicado en: | Open Forum Infect Dis |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6253713/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.794 |
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