126. Robust and Persistent Vaginal Colonization with LACTIN-V Vaginal Lactobacillus crispatus Probiotic in a Double-Blind, Placebo-Controlled (DBPC) Phase 2b Trial to Prevent Recurrent UTI (rUTI)

BACKGROUND: We investigated vaginal colonization using repetitive sequence PCR (repPCR) and 16S rRNA sequencing in a Phase 2b DBPC trial of a L. crispatus intravaginal suppository probiotic for prevention of rUTI in premenopausal women. METHODS: Twenty-four young women with a history of rUTI and cur...

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Publicado en:Open Forum Infect Dis
Main Authors: Stapleton, Ann, Silvestroni, Aurelio, Roberts, Pacita, Cox, Marsha, Hayden, Hillary, Brittnacher, Mitchell, Miller, Samuel, Hooton, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252922/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy209.016
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