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1381. Impact of Total Body Weight on Efficacy of Ceftriaxone in Obese Patients

BACKGROUND: Ceftriaxone (CRO), while highly protein bound, retains a small volume of distribution. Obese patients have larger volumes of distributions and higher clearance than nonobese patients. The effect of these differences on the pharmacokinetics and efficacy of CRO remain unclear. METHODS: Thi...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Wagner, Jamie L, Loper, J Taylor, Morrison, Austin R, Stover, Kayla R, Barber, Katie E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252697/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1212
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