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1381. Impact of Total Body Weight on Efficacy of Ceftriaxone in Obese Patients
BACKGROUND: Ceftriaxone (CRO), while highly protein bound, retains a small volume of distribution. Obese patients have larger volumes of distributions and higher clearance than nonobese patients. The effect of these differences on the pharmacokinetics and efficacy of CRO remain unclear. METHODS: Thi...
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| Vydáno v: | Open Forum Infect Dis |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6252697/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1212 |
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