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1353. In Vitro Activity of Lefamulin (LEF) Against Bacterial Pathogens Commonly Causing Community-Acquired Bacterial Pneumonia (CABP): 2016 SENTRY Data From the United States

BACKGROUND: LEF, the first pleuromutilin antibiotic for IV and oral use in humans, is in Phase 3 clinical trials for the treatment of CABP in adults. In the first of these to be completed, LEF demonstrated noninferiority to moxifloxacin ± linezolid. LEF inhibits bacterial translation by binding the...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Paukner, Susanne, Flamm, Robert K, Gelone, Steven P, Sader, Helio S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252668/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1184
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