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1952. Evaluation of Relapse and Reinfection Using Whole-Genome Sequencing of Clostridium difficile Isolates From Elderly Patients With C. difficile Infection (CDI) in the EXTEND Randomized, Controlled, Comparative Study of Extended-Pulsed Fidaxomicin and Vancomycin for the Treatment of CDI

BACKGROUND: The EXTEND study demonstrated reduced 90-day recurrence rates for an extended-pulsed regimen of fidaxomicin (EPFX) vs. standard vancomycin (SV) in the treatment of Clostridium difficile infection (CDI): treatment difference −13%, P = 0.00073.(1) Whole-genome sequencing (WGS) is used to d...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Open Forum Infect Dis
Κύριοι συγγραφείς: Wilcox, Mark, Cornely, Oliver A, Guery, Benoit, Longshaw, Chris, Georgopali, Areti, Karas, Andreas, Kazeem, Gbenga, Palacios-Fabrega, Jose Alejandro, Vehreschild, Maria J G T
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252577/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1608
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