1952. Evaluation of Relapse and Reinfection Using Whole-Genome Sequencing of Clostridium difficile Isolates From Elderly Patients With C. difficile Infection (CDI) in the EXTEND Randomized, Controlled, Comparative Study of Extended-Pulsed Fidaxomicin and Vancomycin for the Treatment of CDI

BACKGROUND: The EXTEND study demonstrated reduced 90-day recurrence rates for an extended-pulsed regimen of fidaxomicin (EPFX) vs. standard vancomycin (SV) in the treatment of Clostridium difficile infection (CDI): treatment difference −13%, P = 0.00073.(1) Whole-genome sequencing (WGS) is used to d...

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Vydáno v:Open Forum Infect Dis
Hlavní autoři: Wilcox, Mark, Cornely, Oliver A, Guery, Benoit, Longshaw, Chris, Georgopali, Areti, Karas, Andreas, Kazeem, Gbenga, Palacios-Fabrega, Jose Alejandro, Vehreschild, Maria J G T
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252577/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1608
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