Antitumor Activity of Auger Electron Emitter (111)In Delivered by Modular Nanotransporter for Treatment of Bladder Cancer With EGFR Overexpression

Gamma-ray emitting (111)In, which is extensively used for imaging, is also a source of short-range Auger electrons (AE). While exhibiting negligible effect outside cells, these AE become highly toxic near DNA within the cell nucleus. Therefore, these radionuclides can be used as a therapeutic antica...

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發表在:Front Pharmacol
Main Authors: Rosenkranz, Andrey A., Slastnikova, Tatiana A., Karmakova, Tatiana A., Vorontsova, Maria S., Morozova, Natalia B., Petriev, Vasiliy M., Abrosimov, Alexey S., Khramtsov, Yuri V., Lupanova, Tatiana N., Ulasov, Alexey V., Yakubovskaya, Raisa I., Georgiev, Georgii P., Sobolev, Alexander S.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
主題:
Pharmacology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252321/
https://ncbi.nlm.nih.gov/pubmed/30510514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01331
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