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Adjuvant selection regulates gut migration and phenotypic diversity of antigen-specific CD4(+) T cells following parenteral immunization.

Infectious diarrheal diseases are the second leading cause of death in children under five, making vaccines against these diseases a high priority. It is known that certain vaccine adjuvants, chiefly bacterial ADP-ribosylating enterotoxins, can induce mucosal antibodies when delivered parenterally....

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Bibliographic Details
Published in:Mucosal Immunol
Main Authors: Frederick, Daniel R., Goggins, J. Alan, Sabbagh, Leila M., Freytag, Lucy C., Clements, John D., McLachlan, James B.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252260/
https://ncbi.nlm.nih.gov/pubmed/28792004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2017.70
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