Elevated Syndecan-1 after Trauma and Risk of Sepsis: A Secondary Analysis of Patients from the Pragmatic, Randomized Optimal Platelet and Plasma Ratios (PROPPR) Trial

BACKGROUND: Endotheliopathy of trauma is characterized by breakdown of the endothelial glycocalyx. Elevated biomarkers of endotheliopathy, such as serum syndecan-1 (Synd-1) ≥ 40 ng/mL, have been associated with increased need for transfusions, complications, and mortality. We hypothesized that sever...

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Udgivet i:J Am Coll Surg
Main Authors: Wei, Shuyan, Rodriguez, Erika Gonzalez, Chang, Ronald, Holcomb, John B, Kao, Lillian S, Wade, Charles E
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252161/
https://ncbi.nlm.nih.gov/pubmed/30243993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2018.09.003
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