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Target-decoy Based False Discovery Rate Estimation for Large-scale Metabolite Identification

Metabolite identification is a crucial step in mass spectrometry (MS)-based metabolomics. However, it is still challenging to assess the confidence of assigned metabolites. In this study, we report a novel method for estimating false discovery rate (FDR) of metabolite assignment with a target-decoy...

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Bibliografiske detaljer
Udgivet i:J Proteome Res
Main Authors: Wang, Xusheng, Jones, Drew R, Shaw, Timothy I, Cho, Ji-Hoon, Wang, Yuanyuan, Tan, Haiyan, Xie, Boer, Zhou, Suiping, Li, Yuxin, Peng, Junmin
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252074/
https://ncbi.nlm.nih.gov/pubmed/29790753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.8b00019
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