Mitochondrial uncoupler BAM15 inhibits artery constriction and potently activates AMPK in vascular smooth muscle cells

Our previous studies found that mitochondrial uncouplers CCCP and niclosamide inhibited artery constriction and the mechanism involved AMPK activation in vascular smooth muscle cells. BAM15 is a novel type of mitochondrial uncoupler. The aim of the present study is to identify the vasoactivity of BA...

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Bibliographische Detailangaben
Veröffentlicht in:Acta Pharm Sin B
Hauptverfasser: Tai, Yu, Li, Lanjun, Peng, Xuan, Zhu, Junxue, Mao, Xihai, Qin, Nan, Ma, Minghui, Huo, Rong, Bai, Yunlong, Dong, Deli
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
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Original article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251816/
https://ncbi.nlm.nih.gov/pubmed/30505660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2018.07.010
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