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Mitochondria-targeting drug conjugates for cytotoxic, anti-oxidizing and sensing purposes: current strategies and future perspectives

Mitochondrial targeting is a promising approach for solving current issues in clinical application of chemotherapy and diagnosis of several disorders. Here, we discuss direct conjugation of mitochondrial-targeting moieties to anticancer drugs, antioxidants and sensor molecules. Among them, the most...

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Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Battogtokh, Gantumur, Choi, Yeon Su, Kang, Dong Seop, Park, Sang Jun, Shim, Min Suk, Huh, Kang Moo, Cho, Yong-Yeon, Lee, Joo Young, Lee, Hye Suk, Kang, Han Chang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251809/
https://ncbi.nlm.nih.gov/pubmed/30505656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2018.05.006
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