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Media studies to enhance the production of verticillins facilitated by in situ chemical analysis

ABSTRACT: Verticillins are a group of epipolythiodioxopiperazine alkaloids that have displayed potent cytotoxicity. To evaluate their potential further, a larger supply of these compounds was needed for both in vivo studies and analogue development via semisynthesis. To optimize the biosynthesis of...

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Publicado en:J Ind Microbiol Biotechnol
Autores principales: Amrine, Chiraz Soumia M., Raja, Huzefa A., Darveaux, Blaise A., Pearce, Cedric J., Oberlies, Nicholas H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251749/
https://ncbi.nlm.nih.gov/pubmed/30259213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10295-018-2083-8
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