Development of a Dominant Negative Competence Stimulating Peptide (dnCSP) that Attenuates Streptococcus pneumoniae Infectivity in a Mouse Model of Acute Pneumonia

Streptococcus pneumoniae (pneumococcus) is a prevalent human pathogen responsible for a variety of diseases, including pneumonia, bacteremia, sepsis, meningitis and otitis media, with a death toll of >22,000 a year in the United States alone. Pneumococcus utilizes the competence regulon and its a...

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Vydáno v:Chembiochem
Hlavní autoři: Koirala, Bimal, Lin, Jingjun, Lau, Gee W., Tal-Gan, Yftah
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251734/
https://ncbi.nlm.nih.gov/pubmed/30211457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800505
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