ASH1-catalyzed H3K36 methylation drives gene repression and marks H3K27me2/3-competent chromatin

Methylation of histone H3 at lysine 36 (H3K36me), a widely-distributed chromatin mark, largely results from association of the lysine methyltransferase (KMT) SET-2 with RNA polymerase II (RNAPII), but most eukaryotes also have additional H3K36me KMTs that act independently of RNAPII. These include t...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Bicocca, Vincent T, Ormsby, Tereza, Adhvaryu, Keyur K, Honda, Shinji, Selker, Eric U
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Chromosomes and Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251624/
https://ncbi.nlm.nih.gov/pubmed/30468429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41497
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