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NAADP-dependent Ca(2+) signaling regulates Middle East respiratory syndrome-coronavirus pseudovirus translocation through the endolysosomal system

Middle East Respiratory Syndrome coronavirus (MERS-CoV) infections are associated with a significant mortality rate, and existing drugs show poor efficacy. Identifying novel targets/pathways required for MERS infectivity is therefore important for developing novel therapeutics. As an enveloped virus...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Calcium
Hauptverfasser: Gunaratne, Gihan S., Yang, Yang, Li, Fang, Walseth, Timothy F., Marchant, Jonathan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Ltd. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251489/
https://ncbi.nlm.nih.gov/pubmed/30121440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2018.08.003
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