Folate receptor targeting of radiolabeled liposomes reduces intratumoral liposome accumulation in human KB carcinoma xenografts

BACKGROUND: Active, ligand-mediated, targeting of functionalized liposomes to folate receptors (FRs) overexpressed on cancer cells could potentially improve drug delivery and specificity. Studies on folate-targeting liposomes (FTLs) have, however, yielded varying results and generally fail to displa...

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Dades bibliogràfiques
Publicat a:Int J Nanomedicine
Autors principals: Christensen, Esben, Henriksen, Jonas R, Jørgensen, Jesper T, Amitay, Yasmine, Shmeeda, Hilary, Gabizon, Alberto A, Kjær, Andreas, Andresen, Thomas L, Hansen, Anders E
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251465/
https://ncbi.nlm.nih.gov/pubmed/30538449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S182579
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