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Combination of metformin and phenformin synergistically inhibits proliferation and hTERT expression in human breast cancer cells

OBJECTIVE(S): Breast cancer remains a global challenge, and further chemopreventive therapies are still immediately required. Emerging evidence has revealed the potent anti-cancer effects of biguanides, Metformin (MET) and phenformin (PHE). Thus, to explore an efficient chemopreventive strategy for...

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Detalhes bibliográficos
Publicado no:Iran J Basic Med Sci
Main Authors: Jafari-Gharabaghlou, Davoud, Pilehvar-Soltanahmadi, Younes, Dadashpour, Mehdi, Mota, Ali, Vafajouy-Jamshidi, Soheila, Faramarzi, Leila, Rasouli, Sara, Zarghami, Nosratollah
Formato: Artigo
Idioma:Inglês
Publicado em: Mashhad University of Medical Sciences 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251396/
https://ncbi.nlm.nih.gov/pubmed/30483391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2018.30460.7345
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