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The Role of IRE1 Signaling in the Central Nervous System Diseases
The accumulation of misfolded or unfolded proteins in endoplasmic reticulum (ER) lumen results in the activation of an adaptive stress process called the unfolded protein response (UPR). As the most conserved signaling branch of the UPR, Inositol-requiring enzyme 1 (IRE1) possesses both Ser/Thr kina...
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| Publicado en: | Curr Neuropharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Bentham Science Publishers
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6251047/ https://ncbi.nlm.nih.gov/pubmed/29663887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X16666180416094646 |
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