Epigenetically regulated miR-1247 functions as a novel tumour suppressor via MYCBP2 in methylator colon cancers

BACKGROUND: Colorectal cancer (CRC) is a heterogeneous disease with distinct clinical subsets based on underlying genetic and epigenetic changes. DNA hypermethylation yields a unique CRC subset with a distinct phenotype and clinical behaviour, but this oncogenic pathway is not fully characterised. T...

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Bibliografske podrobnosti
izdano v:Br J Cancer
Main Authors: Liang, Jennifer, Zhou, Wenchao, Sakre, Nneha, DeVecchio, Jennifer, Ferrandon, Sylvain, Ting, Angela H., Bao, Shideng, Bissett, Ian, Church, James, Kalady, Matthew F.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251029/
https://ncbi.nlm.nih.gov/pubmed/30318507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0249-9
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