Irradiance controls photodynamic efficacy and tissue heating in experimental tumours: implication for interstitial PDT of locally advanced cancer

BACKGROUND: Currently delivered light dose (J/cm(2)) is the principal parameter guiding interstitial photodynamic therapy (I-PDT) of refractory locally advanced cancer. The aim of this study was to investigate the impact of light dose rate (irradiance, mW/cm(2)) and associated heating on tumour resp...

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Publicado en:Br J Cancer
Autores principales: Shafirstein, Gal, Bellnier, David A., Oakley, Emily, Hamilton, Sasheen, Habitzruther, Michael, Tworek, Lawrence, Hutson, Alan, Spernyak, Joseph A., Sexton, Sandra, Curtin, Leslie, Turowski, Steven G., Arshad, Hassan, Henderson, Barbara
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251027/
https://ncbi.nlm.nih.gov/pubmed/30353043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0210-y
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