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Zinc finger E-box-binding homeobox 1 mediates aerobic glycolysis via suppression of sirtuin 3 in pancreatic cancer

AIM: To uncover the roles of tumor-promoting gene ZEB1 in aerobic glycolysis regulation and shed light on the underlying molecular mechanism. METHODS: Endogenous zinc finger E-box binding homeobox-1 (ZEB1) was silenced using a lentivirus-mediated method, and the impact of ZEB1 and methyl-CpG binding...

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Détails bibliographiques
Publié dans:World J Gastroenterol
Auteurs principaux: Xu, Wen-Yan, Hu, Qiang-Sheng, Qin, Yi, Zhang, Bo, Liu, Wen-Sheng, Ni, Quan-Xing, Xu, Jin, Yu, Xian-Jun
Format: Artigo
Langue:Inglês
Publié: Baishideng Publishing Group Inc 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6250915/
https://ncbi.nlm.nih.gov/pubmed/30487699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v24.i43.4893
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