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A Unified Approach to Couple Aromatic Heteronucleophiles to Azines and Pharmaceuticals.

Coupling aromatic heteronucleophiles to arenes is a common way to assemble drug-like molecules. Many methods operate via nucleophiles intercepting organometallic intermediates, via Pd-, Cu- and Ni-catalysis, that facilitate carbon-heteroatom bond-formation and a variety of protocols. We present an a...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Anderson, Ryan G., Jett, Brianna M., McNally, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6250568/
https://ncbi.nlm.nih.gov/pubmed/30084203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201807322
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