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P7C3-A20 neuroprotection is independent of Wallerian degeneration in primary neuronal culture
The antiapoptotic, neuroprotective compound P7C3-A20 reduces neurological deficits when administered to murine in-vivo models of traumatic brain injury. P7C3-A20 is thought to exert its activity through small-molecule activation of the enzyme nicotinamide phosphoribosyltransferase. This enzyme conve...
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| Publié dans: | Neuroreport |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Lippincott Williams & Wilkins
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6250284/ https://ncbi.nlm.nih.gov/pubmed/30334859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000001146 |
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