Effects of Low- and High-Mineral Content Water on the Relative Bioavailability of a Coformulated Abacavir/Dolutegravir/Lamivudine Dispersible Tablet in Healthy Adults

BACKGROUND: The fixed-dose combination (FDC) tablet formulation of abacavir/dolutegravir/lamivudine is indicated for the treatment of HIV-1 infection in adults and pediatric patients weighing ≥40 kg. Alternative formulations with acceptable palatability and convenient dosing are needed for children...

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Detalhes bibliográficos
Publicado no:J Acquir Immune Defic Syndr
Main Authors: Singh, Rajendra P., Shaik, Jafar S. B., Skoura, Nancy, Joshi, Shashidhar, Shreeves, Trevor, Casillas, Linda, Buchanan, Ann M.
Formato: Artigo
Idioma:Inglês
Publicado em: JAIDS Journal of Acquired Immune Deficiency Syndromes 2018
Assuntos:
Clinical Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6250255/
https://ncbi.nlm.nih.gov/pubmed/30239425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001859
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