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Central masked adjudication of stroke diagnosis at trial entry offered no advantage over diagnosis by local clinicians: Secondary analysis and simulation

BACKGROUND: Central adjudication of stroke type is commonly implemented in large multicentre clinical trials. We investigated the effect of central adjudication of diagnosis of stroke type at trial entry in the Efficacy of Nitric Oxide in Stroke (ENOS) trial. METHODS: ENOS recruited patients with ac...

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Bibliografiske detaljer
Udgivet i:Contemp Clin Trials Commun
Main Authors: Godolphin, Peter J., Hepburn, Trish, Sprigg, Nikola, Walker, Liz, Berge, Eivind, Collins, Ronan, Gommans, John, Ntaios, George, Pocock, Stuart, Prasad, Kameshwar, Wardlaw, Joanna M., Bath, Philip M., Montgomery, Alan A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249966/
https://ncbi.nlm.nih.gov/pubmed/30533551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.conctc.2018.11.002
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