Human UCB-MSCs treatment upon intraventricular hemorrhage contributes to attenuate hippocampal neuron loss and circuit damage through BDNF-CREB signaling

BACKGROUND: Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) have been shown to prevent brain damage and improve neurocognition following intraventricular hemorrhage (IVH). However, the molecular mechanisms underlying the effects of hUCB-MSCs are still elusive. Thus, as the hipp...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res Ther
Main Authors: Ko, Hyo Rim, Ahn, So Yoon, Chang, Yun Sil, Hwang, Inwoo, Yun, Taegwan, Sung, Dong Kyung, Sung, Se In, Park, Won Soon, Ahn, Jee-Yin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249960/
https://ncbi.nlm.nih.gov/pubmed/30463591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1052-5
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