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A constitutive active allele of the transcription factor Msn2 mimicking low PKA activity dictates metabolic remodeling in yeast

In yeast, protein kinase A (PKA) adjusts transcriptional profiles, metabolic rates, and cell growth in accord with carbon source availability. PKA affects gene expression mostly via the transcription factors Msn2 and Msn4, two key regulators of the environmental stress response. Here we analyze the...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Pfanzagl, Vera, Görner, Wolfram, Radolf, Martin, Parich, Alexandra, Schuhmacher, Rainer, Strauss, Joseph, Reiter, Wolfgang, Schüller, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249869/
https://ncbi.nlm.nih.gov/pubmed/30256697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-06-0389
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