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Acquired mechanisms of immune escape in cancer following immunotherapy

Immunotherapy has revolutionized the management of numerous cancers; however, a substantial proportion that initially respond subsequently acquire means of immune escape and relapse. Analysis of recent clinical trials permits us to preliminarily understand how immunotherapies exert evolutionary pres...

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Veröffentlicht in:Genome Med
Hauptverfasser: Bryan Iorgulescu, J., Braun, David, Oliveira, Giacomo, Keskin, Derin B., Wu, Catherine J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249768/
https://ncbi.nlm.nih.gov/pubmed/30466478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-018-0598-2
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