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Co-transplantation of mesenchymal stem cells improves spermatogonial stem cell transplantation efficiency in mice

BACKGROUND: Spermatogonial stem cell transplantation (SSCT) could become a fertility restoration tool for childhood cancer survivors. However, since in mice, the colonization efficiency of transplanted spermatogonial stem cells (SSCs) is only 12%, the efficiency of the procedure needs to be improved...

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Publicado en:Stem Cell Res Ther
Main Authors: Kadam, Prashant, Ntemou, Elissavet, Baert, Yoni, Van Laere, Sven, Van Saen, Dorien, Goossens, Ellen
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249754/
https://ncbi.nlm.nih.gov/pubmed/30463610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1065-0
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