Stress-Induced Low Complexity RNA Activates Physiological Amyloidogenesis

Amyloid bodies (A-bodies) are inducible membraneless nuclear compartments composed of heterogeneous proteins that adopt an amyloid-like state. A-bodies are seeded by noncoding RNA derived from stimuli-specific loci of the rDNA intergenic spacer (rIGSRNA). This raises the question of how rIGSRNA recr...

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Pubblicato in:Cell Rep
Autori principali: Wang, Miling, Tao, Xianzun, Jacob, Mathieu D., Bennett, Clayton A., Ho, J.J. David, Gonzalgo, Mark L., Audas, Timothy E., Lee, Stephen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249693/
https://ncbi.nlm.nih.gov/pubmed/30110628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.07.040
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