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Marburg Virus Viral Protein 35 Inhibits Protein Kinase R Activation in a Cell Type–Specific Manner

Protein kinase R (PKR) is a key antiviral protein involved in sensing and restricting viral infections. Here we analyzed the ability of Marburg virus (MARV) viral protein 35 (VP35) to inhibit PKR activation in human and bat cells. Similar to the related Ebola and Lloviu viruses, MARV VP35 was able t...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Hume, Adam, Mühlberger, Elke
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249588/
https://ncbi.nlm.nih.gov/pubmed/30165526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy473
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