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Glucocorticoids affect bone mineral density and bone remodelling in OVX sheep: A pilot study

The aim of this study was to validate the combination of ovariectomy and glucocorticoid treatment in sheep as a large animal model for osteoporosis by measuring the concentration of specific biomarkers in the blood of the sheep and measuring bone loss over five months. Aged Merino ewes were randomly...

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Publicado en:Bone Rep
Main Authors: Cabrera, Diana, Wolber, Frances M., Dittmer, Keren, Rogers, Chris, Ridler, Anne, Aberdein, Danielle, Parkinson, Tim, Chambers, Paul, Fraser, Karl, Roy, Nicole C., Kruger, Marlena
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249392/
https://ncbi.nlm.nih.gov/pubmed/30480061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bonr.2018.11.001
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