HLA Polymorphism Affects Risk of de novo Mutation of dystrophin Gene and Clinical Severity of Duchenne Muscular Dystrophy in a Southern Chinese Population

Immune-mediated pathology has been thought to be an important factor contributing to Duchenne muscular dystrophy (DMD). Allele frequencies of certain HLA types are known to differ between patients with dystrophinopathies and healthy controls with low-resolution HLA gene typing data in limit reports....

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Bibliografische gegevens
Gepubliceerd in:Front Neurol
Hoofdauteurs: Li, Huan, Xiao, Lulu, Wang, Liang, Lin, Jinfu, Luo, Min, Chen, Menglong, He, Ruojie, Zhu, Yuling, Zhang, Cheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2018
Onderwerpen:
Neurology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249334/
https://ncbi.nlm.nih.gov/pubmed/30498470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2018.00970
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