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B CELL PHENOTYPES IN BABOONS WITH PIG ARTERY PATCH GRAFTS RECEIVING CONVENTIONAL IMMUNOSUPPRESSIVE THERAPY

BACKGROUND: In the pig-to-baboon artery patch model with no immunosuppressive therapy, a graft from an α1, 3-galactosyltransferase gene-knockout (GTKO) pig elicits a significant anti-nonGal IgG response, indicating sensitization to the graft. A costimulation blockade-based regimen, e.g., anti-CD154m...

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Bibliographische Detailangaben
Veröffentlicht in:Transpl Immunol
Hauptverfasser: Yamamoto, Takayuki, Li, Qi, Hara, Hidetaka, Wang, Liaoran, Zhou, Hongmin, Li, Juan, Eckhoff, Devin E., Joseph Tector, A., Klein, Edwin C., Lovingood, Ray, Ezzelarab, Mohamed, Ayares, David, Wang, Yi, Cooper, David K.C., Iwase, Hayato
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249078/
https://ncbi.nlm.nih.gov/pubmed/30092338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trim.2018.08.005
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