Development of Positron Emission Tomography (PET) Radiotracers for the GABA Transporter 1 (GAT-1)

In vivo PET imaging of the γ-aminobutyric acid (GABA) receptor complex has been accomplished using radiolabeled benzodiazepine derivatives, but development of specific presynaptic radioligands targeting the neuronal membrane GABA transporter type 1 (GAT-1) has been less successful. The availability...

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Publicat a:ACS Chem Neurosci
Autors principals: Sowa, Alexandra R., Brooks, Allen F., Shao, Xia, Henderson, Bradford D., Sherman, Philip, Arteaga, Janna, Stauff, Jenelle, Lee, Adam C., Koeppe, Robert A., Scott, Peter J. H., Kilbourn, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249062/
https://ncbi.nlm.nih.gov/pubmed/29763549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.8b00183
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