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The role of Xist in X-chromosome dosage compensation

In each somatic cell of a female mammal one X chromosome is transcriptionally silenced via X-chromosome inactivation (XCI), initiating early in development. Although XCI events are conserved in mouse and human post-implantation development, regulation of X-chromosome dosage in pre-implantation devel...

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Detalhes bibliográficos
Publicado no:Trends Cell Biol
Main Authors: Sahakyan, Anna, Yang, Yihao, Plath, Kathrin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249047/
https://ncbi.nlm.nih.gov/pubmed/29910081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2018.05.005
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