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Efficient synthesis of light-triggered circular antisense oligonucleotides targeting cellular protein expression

Light-activated (“caged”) antisense oligonucleotides are powerful molecules for regulating gene expression at sub-micron spatial resolution, through the focal modulation of endogenous cellular processes. Cyclized caged oligos are particularly promising structures based on their inherent stability an...

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Dades bibliogràfiques
Publicat a:Chembiochem
Autors principals: Yang, Linlin, Kim, Hyun-Bum, Sul, Jai-Yoon, Yeldell, Sean B., Eberwine, James H., Dmochowski, Ivan J.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248878/
https://ncbi.nlm.nih.gov/pubmed/29479781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800012
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