Integrative analysis identifies co-dependent gene expression regulation of BRG1 and CHD7 at distal regulatory sites in embryonic stem cells

MOTIVATION: DNA binding proteins such as chromatin remodellers, transcription factors (TFs), histone modifiers and co-factors often bind cooperatively to activate or repress their target genes in a cell type-specific manner. Nonetheless, the precise role of cooperative binding in defining cell-type...

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Publicat a:Bioinformatics
Autors principals: Yang, Pengyi, Oldfield, Andrew, Kim, Taiyun, Yang, Andrian, Yang, Jean Yee Hwa, Ho, Joshua W K
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Discovery Notes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248803/
https://ncbi.nlm.nih.gov/pubmed/28203701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btx092
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