Negative Correlation Between Hepatitis C Virus (HCV) and Let-7 MicroRNA Family in Transplanted Livers: The Role of rs868 Single-Nucleotide Polymorphism

BACKGROUND: Genetic alterations of TGF-β pathway members, including its transmembrane receptor, TGFBR1, may influence the course of HCV infection. Rs868 is a single-nucleotide polymorphism of the 3′UTR region of TGFBR1, located in a binding site for the conserved let-7/miR98 microRNA family. Previou...

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Publicado en:Ann Transplant
Autores principales: Sajjad, Emir Ahmed, Radkowski, Marek, Perkowska-Ptasińska, Agnieszka, Pacholczyk, Marek, Durlik, Magdalena, Fedorowicz, Mikołaj, Pietrzak, Renata, Ziarkiewicz-Wróblewska, Bogna, Włodarski, Paweł, Malejczyk, Jacek
Formato: Artigo
Lenguaje:Inglês
Publicado: International Scientific Literature, Inc. 2017
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Original Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248281/
https://ncbi.nlm.nih.gov/pubmed/29061957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/AOT.905540
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