Gene transfer to rat cerebral cortex mediated by polysorbate 80 and poloxamer 188 nonionic surfactant vesicles

BACKGROUND: Gene therapy can be an intriguing therapeutic option in wide-ranging neurological disorders. Though nonviral gene carriers represent a safer delivery system to their viral counterparts, a thorough design of such vehicles is crucial to enhance their transfection properties. PURPOSE: This...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Attia, Noha, Mashal, Mohamed, Soto-Sánchez, Cristina, Martínez-Navarrete, Gema, Fernández, Eduardo, Grijalvo, Santiago, Eritja, Ramón, Puras, Gustavo, Pedraz, Jose Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248232/
https://ncbi.nlm.nih.gov/pubmed/30510402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S178532
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