Effect of Cannabidiol on Medial Temporal, Midbrain, and Striatal Dysfunction in People at Clinical High Risk of Psychosis: A Randomized Clinical Trial

IMPORTANCE: Cannabidiol (CBD) has antipsychotic effects in humans, but how these are mediated in the brain remains unclear. OBJECTIVE: To investigate the neurocognitive mechanisms that underlie the therapeutic effects of CBD in psychosis. DESIGN, SETTING, AND PARTICIPANTS: In this parallel-group, do...

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Detalhes bibliográficos
Publicado no:JAMA Psychiatry
Main Authors: Bhattacharyya, Sagnik, Wilson, Robin, Appiah-Kusi, Elizabeth, O’Neill, Aisling, Brammer, Michael, Perez, Jesus, Murray, Robin, Allen, Paul, Bossong, Matthijs G., McGuire, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2018
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248101/
https://ncbi.nlm.nih.gov/pubmed/30167644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamapsychiatry.2018.2309
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