Association of Transforming Growth Factor β Polymorphism C−509T With Radiation-Induced Fibrosis Among Patients With Early-Stage Breast Cancer: A Secondary Analysis of a Randomized Clinical Trial

IMPORTANCE: Whether genetic factors can identify patients at risk for radiation-induced fibrosis remains unconfirmed. OBJECTIVE: To assess the association between the C−509T variant allele in the promoter region of TGFB1 and breast fibrosis 3 years after radiotherapy. DESIGN, SETTING, AND PARTICIPAN...

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Dettagli Bibliografici
Pubblicato in:JAMA Oncol
Autori principali: Grossberg, Aaron J., Lei, Xiudong, Xu, Ting, Shaitelman, Simona F., Hoffman, Karen E., Bloom, Elizabeth S., Stauder, Michael C., Tereffe, Welela, Schlembach, Pamela J., Woodward, Wendy A., Buchholz, Thomas A., Smith, Benjamin D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Medical Association 2018
Soggetti:
Original Investigation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248087/
https://ncbi.nlm.nih.gov/pubmed/30027292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.2583
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