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GateFinder: projection-based gating strategy optimization for flow and mass cytometry

MOTIVATION: High-parameter single-cell technologies can reveal novel cell populations of interest, but studying or validating these populations using lower-parameter methods remains challenging. RESULTS: Here, we present GateFinder, an algorithm that enriches high-dimensional cell types with simple,...

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Publicat a:Bioinformatics
Autors principals: Aghaeepour, Nima, Simonds, Erin F, Knapp, David J H F, Bruggner, Robert V, Sachs, Karen, Culos, Anthony, Gherardini, Pier Federico, Samusik, Nikolay, Fragiadakis, Gabriela K, Bendall, Sean C, Gaudilliere, Brice, Angst, Martin S, Eaves, Connie J, Weiss, William A, Fantl, Wendy J, Nolan, Garry P
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247943/
https://ncbi.nlm.nih.gov/pubmed/29850785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty430
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