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Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis

During embryogenesis, cells acquire distinct fates by transitioning through transcriptional states. To uncover these transcriptional trajectories during zebrafish embryogenesis, we sequenced 38,731 cells and developed URD, a simulated diffusion-based computational reconstruction method. URD identifi...

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Foilsithe in:Science
Main Authors: Farrell, Jeffrey A., Wang, Yiqun, Riesenfeld, Samantha J., Shekhar, Karthik, Regev, Aviv, Schier, Alexander F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247916/
https://ncbi.nlm.nih.gov/pubmed/29700225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar3131
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